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Discuss with your healthcare provider the best ways to manage your B12 levels, which may include dietary supplements or fortified foods like breakfast cereals

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The N-terminal acetylation and C-terminal amide are both structural features important for MC1R binding geometry

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Bottom line on oral bioavailability: The expectation based on peptide pharmacokinetics is that the majority of intact TB-500 is degraded in the GI tract before reaching systemic circulation